Computer and Information Science
“Probe and Probe Sets”
Dr. Hongfang Liu
Department of Biostatistics, Bioinformatics
And Biomathematics (DBBB)
School of Medicine Georgetown University
Date : Friday, April 7, 2006
Location : Lincoln Center Campus – LL 816
Affymetrix microarrays are widely used to measure the global expression of the mRNA transcripts of an organism’s genome. Affymetrix technology is based upon the concept of a /probe set/. All of the individual probes within a probe set are presumed to hybridize to the same unique mRNA transcript. However, the grouping of probes into probe sets is currently based on what the designers wish to measure not based on what they are actually measuring. In this talk I will discuss the bioinformatics resources developed to target the problem as well as challenges faced.
Hongfang Liu, Ph.D., is currently an assistant professor in the Department of Biostatistics, Bioinformatics, and Biomathematics (DBBB) of Georgetown University. Prior to that, she worked in the Information Systems department of University of Maryland at Baltimore County as an assistant professor. Her research interests include bioinformatics, medical informatics, machine learning, data mining, and biomedical text mining. Liu received a B.S. degree in Applied Mathematics and Statistics from University of Science and Technology in China in 1994, an M.S. degree in Computer Science from Fordham University in 1998, a Ph.D. degree in Computer Science at the Graduate School of City University of New York in 2002. Contact her at the DBBB, Georgetown University Medical Center, Washington, DC 20007; firstname.lastname@example.org.
For more information or directions, contact Ms. Diane Roche (718) 817-4480